The Federal Institute for Risk Assessment (BfR) is the national institute which prepares expert reports and opinions on questions concerning the safety of food, feed and chemicals, as well as consumer health protection, on the basis of internationally recognised scientific evaluation criteria. It advises the Federal Government and other institutions and interest groups in these areas. The BfR conducts its own research on topics that are closely linked to its assessment tasks. It is an institution with legal capacity within the portfolio of the Federal Ministry of Food and Agriculture (BMEL).
The BfR is setting up junior research groups to set strategic priorities. Scientists are to be offered attractive opportunities to conduct research and gain scientific qualifications at the BfR. The following position is to be filled with immediate effect for a period of three years in the Exposure department at the BfR in the “Toxicokinetic Modelling” junior research group (Physiologically based toxicokinetic modelling):
Junior Research Group Leader
- Salary group 14 TVöD -
Reference number: 1661/2017
Part-time work is possible.
The limited employment period is based on the German Fixed-Term Research Contracts Act (Wissenschaftszeitvertragsgesetz).
Employment is within the scope of the establishment of junior research groups at the BfR for a period of three years. After 3 years, the junior research groups will be evaluated on the basis of their scientific performance with the option of extending for a further period of two years.
- The range of duties comprises the modelling of food risks and chemicals with physiologically based models (PBTK), model validation and the use of epidemiological data in modelling.
- Sound knowledge of the distribution and transport of chemicals in organisms and mechanistic understanding of the physico-chemical principles of toxicokinetics form the basis.
- Conducting of PBTK modelling on selected substances
- Development of a strategy for the validation of PBTK models
- Validation of various PBTK models and conception of a database on various models for use in risk assessment at the Institute
- Examination of the suitability of various deep detail models
- Examinations of variability and uncertainty in PBTK models
- Conceptual further development and application of physiologically based toxicokinetic models in the context of risk assessments at the BfR
- Expert opinions on PBTK models
- Development of guidelines for use
- Heading of a junior research group and supervision of two doctoral theses in this field; exchange with international scientists and support with further training events
- Doctorate in Mathematics, Physics, Pharmacy, Medicine, Veterinary Medicine, Bioinformatics, Biology or comparable subject with the necessary specialisation and/or additional training
- Documented professional experience and very profound knowledge of modelling, mathematics, informatics or physics, as well as experience and knowledge in a discipline associated with risk assessment at the Institute (e.g. pharmacology, chemistry, toxicology, epidemiology, biology, veterinary and human medicine)
- Sound knowledge of the distribution and transport of chemicals in organisms and mechanistic understanding of the physico-chemical principles of toxicokinetics are a prerequisite
- Knowledge of PBTK modelling
- Knowledge of software and software programs for PBTK modelling essential
- Knowledge of one programming language or software program (Python, Matlab, Mathematica etc.) and a statistical software (R, SAS, J MP etc.) preferred
- Experience in the instruction of a scientific team and the successful acquisition of research funding of advantage
- Very good knowledge of data processing programs preferred
- Experience of committee work on national and international level preferred
- Very good written and spoken English
- Good computer literacy as well as a conscientious work approach, flexibility, ability to work in a team and the ability to cope with pressure are prerequisites
The place of work is Berlin.
More detailed information is available from PD Dr. Christine Müller-Graf (Tel.: 030 18412 -1912) and Prof. Dr. Matthias Greiner (Tel.: 030 18412-3297).
The BfR welcomes applications from people of all nationalities. The BfR is an innovative scientific institute offering family-friendly working conditions and was awarded the "audit berufundfamilie®" (work and family) certificate. The BfR guarantees equal career opportunities for women and men, and is therefore particularly interested in receiving applications from women. In the case of equal suitability, severely disabled applicants will be given preferential consideration and are only required to have a minimum level of physical suitability.
Does this appeal to you?
Then please submit your application via our online system by 20 March 2017: https://apps.bfr.bund.de/dbv3n/web/StartApply.do .
Please direct any questions you may have regarding the application procedure to: firstname.lastname@example.org .
Please do not send any applications to this e-mail address.
If you are unable to submit your application online, you have the option of sending it by standard mail, stating the relevant reference number
(Bundesinstitut für Risikobewertung, Personalreferat – 11.17 -, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany).